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Product > Antibody > CEBPB Monoclonal Antibody
CEBPB Monoclonal Antibody
CEBPB Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3H9
Host: Mouse
Reactivity:Human
Applications: FCM
Product Summary
Size:
50μL
Clonality: 3H9
Host: Mouse
Reactivity: Human
Applications: FCM
Product overview
Code
BT-MCA2924
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3H9
Immunogen
Purified recombinant fragment of human CEBPB expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.
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