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Product > Antibody > FOXP2 Monoclonal Antibody
FOXP2 Monoclonal Antibody
FOXP2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5C11A8
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 5C11A8
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4745
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5C11A8
Immunogen
Purified recombinant fragment of human MAPK3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
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