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Product > Antibody > G6PD Monoclonal Antibody
G6PD Monoclonal Antibody
G6PD Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5E12
Host: Mouse
Reactivity:Human
Applications: WB,IHC,FCM
Product Summary
Size:
50μL
Clonality: 5E12
Host: Mouse
Reactivity: Human
Applications: WB,IHC,FCM
Product overview
Code
BT-MCA2162
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5E12
Immunogen
Purified recombinant fragment of human G6PD expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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