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Product > Antibody > NQO1 Monoclonal Antibody
NQO1 Monoclonal Antibody
NQO1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1A11
Host: Mouse
Reactivity:Human
Applications: WB,FCM
Product Summary
Size:
50μL
Clonality: 1A11
Host: Mouse
Reactivity: Human
Applications: WB,FCM
Product overview
Code
BT-MCA3158
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1A11
Immunogen
Purified recombinant fragment of human NQO1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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