Code
BT-MCA2261
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5D7
Immunogen
Purified recombinant fragment of human HSP27 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). (provided by RefSeq) Tissue specificity: Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.
Uniprot accession
Molecular weight
27kDa
Gene ID
3315
Synonyms
CMT2F;HMN2B;HSP27;HSP28;Hsp25;SRP27;HS.76067;DKFZp586P1322;HSPB1
Research area
Others
Target protein
HSP27
