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Product > Antibody > CRKL Monoclonal Antibody
CRKL Monoclonal Antibody
CRKL Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5E12
Host: Mouse
Reactivity:Human
Applications: FCM
Product Summary
Size:
50μL
Clonality: 5E12
Host: Mouse
Reactivity: Human
Applications: FCM
Product overview
Code
BT-MCA3155
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5E12
Immunogen
Purified recombinant fragment of human CRKL expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
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