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Product > Antibody > XRCC5 Monoclonal Antibody
XRCC5 Monoclonal Antibody
XRCC5 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5C5
Host: Mouse
Reactivity:Human, Mouse
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 5C5
Host: Mouse
Reactivity: Human,Mouse
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA2525
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5C5
Immunogen
Purified recombinant fragment of human XRCC5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
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