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Home >
Product > Antibody > OCT-4 Monoclonal Antibody
OCT-4 Monoclonal Antibody
OCT-4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5F7
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 5F7
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3315
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5F7
Immunogen
Synthesized peptide of human Oct4.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
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