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Product > Antibody > SMAD5 Monoclonal Antibody
SMAD5 Monoclonal Antibody
SMAD5 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3H9
Host: Mouse
Reactivity:Human, Rat
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 3H9
Host: Mouse
Reactivity: Human,Rat
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA4231
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3H9
Immunogen
Purified recombinant fragment of human SMAD5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
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