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Product > Antibody > NR3C1 Monoclonal Antibody
NR3C1 Monoclonal Antibody
NR3C1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 6E6
Host: Mouse
Reactivity:Human
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 6E6
Host: Mouse
Reactivity: Human
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA2634
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
6E6
Immunogen
Purified recombinant fragment of human NR3C1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Tissue specificity: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
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