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Product > Antibody > ATF2 Monoclonal Antibody
ATF2 Monoclonal Antibody
ATF2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 4F12
Host: Mouse
Reactivity:Human, Mouse
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 4F12
Host: Mouse
Reactivity: Human,Mouse
Applications: WB,IHC
Product overview
Code
BT-MCA2473
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
4F12
Immunogen
Purified recombinant fragment of human ATF2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
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