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Product > Antibody > MAP2K6 Monoclonal Antibody
MAP2K6 Monoclonal Antibody
MAP2K6 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3H12B9
Host: Mouse
Reactivity:Human, Mouse
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 3H12B9
Host: Mouse
Reactivity: Human,Mouse
Applications: WB,IHC
Product overview
Code
BT-MCA3984
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3H12B9
Immunogen
Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.
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