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Home >
Product > Antibody > MAP2K4 Monoclonal Antibody
MAP2K4 Monoclonal Antibody
MAP2K4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5H4
Host: Mouse
Reactivity:Human
Applications: WB,IHC,FCM
Product Summary
Size:
50μL
Clonality: 5H4
Host: Mouse
Reactivity: Human
Applications: WB,IHC,FCM
Product overview
Code
BT-MCA2146
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5H4
Immunogen
Purified recombinant fragment of human MAP2K4 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues .
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