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Product > Antibody > RUNX1 Monoclonal Antibody
RUNX1 Monoclonal Antibody
RUNX1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5A1
Host: Mouse
Reactivity:Human
Applications: WB,ICC
Product Summary
Size:
50μL
Clonality: 5A1
Host: Mouse
Reactivity: Human
Applications: WB,ICC
Product overview
Code
BT-MCA2144
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5A1
Immunogen
Synthesized peptide of human RUNX1.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
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