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Product > Antibody > CTTN Monoclonal Antibody
CTTN Monoclonal Antibody
CTTN Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 4C6
Host: Mouse
Reactivity:Human, Mouse
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 4C6
Host: Mouse
Reactivity: Human,Mouse
Applications: WB,IHC
Product overview
Code
BT-MCA3466
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
4C6
Immunogen
Purified recombinant fragment of human CTTN expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)
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