SMAD6 Monoclonal Antibody

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Home > Product > Antibody > SMAD6 Monoclonal Antibody

SMAD6 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB

Product overview

Code

BT-MCA2396

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human SMAD6 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue.

Uniprot accession

O43541:;

Molecular weight

53kDa

Gene ID

4091

Synonyms

MADH6;MADH7;HsT17432;SMAD6

Research area

Signal Transduction

Target protein

SMAD6

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
ELISA	1:10000

Images

Western blot analysis using SMAD6 mouse mAb against A431 (1), A431 (2), Hela (3) and Jurkat (4) cell lysate.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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