We use cookies to give you the best experience. By using bt-laboratory.com, you
consent to our use of cookies. If you do not wish to receive our cookies, adjust your browser settings. Read
our Cookies
Policy to learn more.
Reject All
Accept All Cookies
We use cookies to give you the best experience. By using bt-laboratory.com,
you consent to our use of cookies. If you do not wish to receive our cookies, adjust your browser settings.
Read our Cookies
Policy to learn more.
Home >
Product > Antibody > CD86 Monoclonal Antibody
CD86 Monoclonal Antibody
CD86 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1B3
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 1B3
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3775
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1B3
Immunogen
Purified recombinant fragment of human CD86 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.