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Product > Antibody > KLHL1 Monoclonal Antibody
KLHL1 Monoclonal Antibody
KLHL1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A8
Host: Mouse
Reactivity:Human
Applications: ICC
Product Summary
Size:
50μL
Clonality: 3A8
Host: Mouse
Reactivity: Human
Applications: ICC
Product overview
Code
BT-MCA4706
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A8
Immunogen
Purified recombinant fragment of human KLHL1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.
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