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Home > Product > Antibody > KLHL1 Monoclonal Antibody

KLHL1 Monoclonal Antibody

KLHL1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: ICC

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: ICC

Product overview

Code

BT-MCA4706

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human KLHL1 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.

Uniprot accession

Molecular weight

82kDa

Gene ID

57626

Synonyms

MRP2;FLJ30047;KIAA1490;KLHL1

Research area

Cell biology

Target protein

KLHL1

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ICC 1:200 - 1:1000
ELISA 1:10000

Images

Western blot analysis using KLHL1 mAb against human KLHL1 (AA: 202-506) recombinant protein. (Expected MW is 60.2 kDa)
Immunofluorescence analysis of NIH/3T3 cells using KLHL1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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