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Product > Antibody > EIF2AK3 Monoclonal Antibody
EIF2AK3 Monoclonal Antibody
EIF2AK3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5G5
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 5G5
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA3889
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5G5
Immunogen
Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
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