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Product > Antibody > CSK Monoclonal Antibody
CSK Monoclonal Antibody
CSK Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5F3
Host: Mouse
Reactivity:Human, Mouse, Monkey, Rat
Applications: WB,ICC,FCM
Product Summary
Size:
50μL
Clonality: 5F3
Host: Mouse
Reactivity: Human,Mouse,Monkey,Rat
Applications: WB,ICC,FCM
Product overview
Code
BT-MCA4035
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5F3
Immunogen
Purified recombinant fragment of human CSK expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity: Expressed in lung and macrophages.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.
