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Product > Antibody > STAT3 Monoclonal Antibody
STAT3 Monoclonal Antibody
STAT3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3B5
Host: Mouse
Reactivity:Human, Mouse, Monkey
Applications: IHC,ICC
Product Summary
Size:
50μL
Clonality: 3B5
Host: Mouse
Reactivity: Human,Mouse,Monkey
Applications: IHC,ICC
Product overview
Code
BT-MCA2556
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3B5
Immunogen
Purified recombinant fragment of human STAT3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3a (86 kDa) and Stat3
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.
