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Home > Product > Antibody > TNFRSF11B Monoclonal Antibody

TNFRSF11B Monoclonal Antibody

TNFRSF11B Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: ICC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: ICC,FCM

Product overview

Code

BT-MCA3726

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Uniprot accession

Molecular weight

60kDa

Gene ID

4982

Synonyms

OPG;TR1;OCIF;MGC29565;TNFRSF11B

Research area

Cardiovascular

Target protein

TNFRSF11B

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
ICC 1:200 - 1:1000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B(AA: 22-401)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis of HL-60 cells using TNFRSF11B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Flow cytometric analysis of HL-60 cells using TNFRSF11B mouse mAb (green) and negative control (purple).

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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