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Product > Antibody > TNFRSF11B Monoclonal Antibody
TNFRSF11B Monoclonal Antibody
TNFRSF11B Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5A11
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 5A11
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA2893
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5A11
Immunogen
Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
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