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Product > Antibody > KLHL12 Monoclonal Antibody
KLHL12 Monoclonal Antibody
KLHL12 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2G2
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 2G2
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3618
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2G2
Immunogen
Purified recombinant fragment of human KLHL12 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
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