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Product > Antibody > ALPP Monoclonal Antibody
ALPP Monoclonal Antibody
ALPP Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3E5
Host: Mouse
Reactivity:Human
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 3E5
Host: Mouse
Reactivity: Human
Applications: WB,IHC
Product overview
Code
BT-MCA4043
Host
Mouse
Isotype
Mouse IgG2b
Size
50μL
Clonality
3E5
Immunogen
Purified recombinant fragment of human ALPP expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
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