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Product > Antibody > WDR5 Monoclonal Antibody
WDR5 Monoclonal Antibody
WDR5 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 7B11
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 7B11
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA4591
Host
Mouse
Isotype
Mouse IgG2b
Size
50μL
Clonality
7B11
Immunogen
Purified recombinant fragment of human WDR5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.
