BT-MCA2160

Mouse

Mouse IgG1

100μL,50μL

Monoclonal

Purified recombinant fragment of human PTK7 expressed in E. Coli.

Ascitic fluid containing 0.03% sodium azide.

Store at 4°C short term. Aliquot and store at -20°C long term.

Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Q13308:;

118kDa

5754

CCK4;PTK7

Tags &,Cell Markers,Signal Transduction,Metabolism

PTK7