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Product > Antibody > HK1 Monoclonal Antibody
HK1 Monoclonal Antibody
HK1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A10
Host: Mouse
Reactivity:Human, Mouse, Rat
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 3A10
Host: Mouse
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA2485
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A10
Immunogen
Purified recombinant fragment of human HK1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.
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