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Product > Antibody > AKT2 Monoclonal Antibody
AKT2 Monoclonal Antibody
AKT2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1B6
Host: Mouse
Reactivity:Human, Rat, Monkey
Applications: WB,IHC,ICC
Product Summary
Size:
50μL
Clonality: 1B6
Host: Mouse
Reactivity: Human,Rat,Monkey
Applications: WB,IHC,ICC
Product overview
Code
BT-MCA4701
Host
Mouse
Isotype
Mouse IgG2b
Size
50μL
Clonality
1B6
Immunogen
Purified recombinant fragment of human AKT2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.
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