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Home >
Product > Antibody > OCT-4 Monoclonal Antibody
OCT-4 Monoclonal Antibody
OCT-4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A5
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 3A5
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4153
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A5
Immunogen
Purified recombinant fragment of OCT4 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation. Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.
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