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Product > Antibody > MATK Monoclonal Antibody
MATK Monoclonal Antibody
MATK Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 9D7
Host: Mouse
Reactivity:Human
Applications: WB,FCM
Product Summary
Size:
50μL
Clonality: 9D7
Host: Mouse
Reactivity: Human
Applications: WB,FCM
Product overview
Code
BT-MCA4533
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
9D7
Immunogen
Purified recombinant fragment of human MATK expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
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