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Product > Antibody > BMP4 Monoclonal Antibody
BMP4 Monoclonal Antibody
BMP4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 10F4B4
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 10F4B4
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA3394
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
10F4B4
Immunogen
Purified recombinant fragment of human BMP4 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
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