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Product > Antibody > FABP2 Monoclonal Antibody
FABP2 Monoclonal Antibody
FABP2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 9A9B7B3
Host: Mouse
Reactivity:Human
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 9A9B7B3
Host: Mouse
Reactivity: Human
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA4799
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
9A9B7B3
Immunogen
Purified recombinant fragment of human FABP2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.
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