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Product > Antibody > CHD3 Monoclonal Antibody
CHD3 Monoclonal Antibody
CHD3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2G4
Host: Mouse
Reactivity:Human, Mouse
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 2G4
Host: Mouse
Reactivity: Human,Mouse
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA3628
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2G4
Immunogen
Purified recombinant fragment of human CHD3 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
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