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Product > Antibody > HDAC4 Monoclonal Antibody
HDAC4 Monoclonal Antibody
HDAC4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 7B2
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 7B2
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA2920
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
7B2
Immunogen
Purified recombinant fragment of human HDAC4 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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