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Product > Antibody > FGB Monoclonal Antibody
FGB Monoclonal Antibody
FGB Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1F9
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 1F9
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA3723
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1F9
Immunogen
Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
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