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Product > Antibody > PAK2 Monoclonal Antibody
PAK2 Monoclonal Antibody
PAK2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3B5
Host: Mouse
Reactivity:Human, Monkey
Applications: WB,IHC,ICC
Product Summary
Size:
50μL
Clonality: 3B5
Host: Mouse
Reactivity: Human,Monkey
Applications: WB,IHC,ICC
Product overview
Code
BT-MCA3569
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3B5
Immunogen
Purified recombinant fragment of PAK2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
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