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Product > Antibody > RTN3 Monoclonal Antibody
RTN3 Monoclonal Antibody
RTN3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 10A8
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 10A8
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA4013
Host
Mouse
Isotype
Mouse IgG2a
Size
50μL
Clonality
10A8
Immunogen
Purified recombinant fragment of RTN3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
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