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Product > Antibody > PGR Monoclonal Antibody
PGR Monoclonal Antibody
PGR Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 8A11H1
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 8A11H1
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4175
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
8A11H1
Immunogen
Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
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