Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > Antibody > PEG10 Monoclonal Antibody

PEG10 Monoclonal Antibody

PEG10 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: IHC

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: IHC

Product overview

Code

BT-MCA3493

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human PEG10 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

Uniprot accession

Molecular weight

Isoform RF1 (37kDa)|RF1/RF2 (80kDa)

Gene ID

23089

Synonyms

Edr;HB-1;Mar2;MEF3L;Mart2;RGAG3

Research area

Epigenetics and nuclear signaling,Stem cells,Cancer

Target protein

PEG10

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
IHC-p 1:200 - 1:1000
ELISA 1:10000

Images

Western blot analysis using PEG10 mouse mAb against HepG2 (1), SMMC-7721 (2) and A549 (3) cell lysate.
Immunohistochemical analysis of paraffin-embedded human hepatocarcinoma (A), breast carcinoma (B) and lung cancer tissues (C), showing cytoplasmic localization with DAB staining using PEG10 mouse mAb.
Immunohistochemical analysis of paraffin-embedded human Placenta tissues using PEG10 mouse mAb

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

Add to Cart

Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up