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Home > Product > Antibody > PAR4 Monoclonal Antibody

PAR4 Monoclonal Antibody

PAR4 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB,IHC

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB,IHC

Product overview

Code

BT-MCA2683

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

Uniprot accession

Gene ID

5074

Synonyms

PAWR

Research area

Others

Target protein

PAR4

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
IHC-p 1:200 - 1:1000
ELISA 1:10000

Images

Western blot analysis using PAR4 mouse mAb against full-length Trx-Par4 recombinant protein (1) and Hela cell lysate (2).
Immunohistochemical analysis of paraffin-embedded human brain (left) and breast carcinoma (right), showing cytoplasmic and membrane localization using PAR4 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human Small Intestine tissues using PAR4 mouse mAb

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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