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Product > Antibody > EphB4 Monoclonal Antibody
EphB4 Monoclonal Antibody
EphB4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 7H4A6
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 7H4A6
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA2403
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
7H4A6
Immunogen
Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
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