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Product > Antibody > PARL Monoclonal Antibody
PARL Monoclonal Antibody
PARL Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 8C4B2
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 8C4B2
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4436
Host
Mouse
Isotype
Mouse IgG2b
Size
50μL
Clonality
8C4B2
Immunogen
Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
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