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Product > Antibody > MDM4 Monoclonal Antibody
MDM4 Monoclonal Antibody
MDM4 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2D10F4
Host: Mouse
Reactivity:Human
Applications: IHC,ICC
Product Summary
Size:
50μL
Clonality: 2D10F4
Host: Mouse
Reactivity: Human
Applications: IHC,ICC
Product overview
Code
BT-MCA3238
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2D10F4
Immunogen
Purified recombinant fragment of human MDM4 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.
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