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Product > Antibody > AXL Monoclonal Antibody
AXL Monoclonal Antibody
AXL Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1B3A2
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 1B3A2
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA3979
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1B3A2
Immunogen
Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
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