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Home >
Product > Antibody > HDAC3 Monoclonal Antibody
HDAC3 Monoclonal Antibody
HDAC3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A7B5
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 3A7B5
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA3164
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A7B5
Immunogen
Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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