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Product > Antibody > MSH6 Monoclonal Antibody
MSH6 Monoclonal Antibody
MSH6 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A10H7
Host: Mouse
Reactivity:Human
Applications:
Product Summary
Size:
50μL
Clonality: 3A10H7
Host: Mouse
Reactivity: Human
Applications:
Product overview
Code
BT-MCA4287
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A10H7
Immunogen
Purified recombinant fragment of MSH6 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.
