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Product > Antibody > SNCG(BCSG1) Monoclonal Antibody
SNCG(BCSG1) Monoclonal Antibody
SNCG(BCSG1) Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 1H10D2
Host: Mouse
Reactivity:Human
Applications: IHC
Product Summary
Size:
50μL
Clonality: 1H10D2
Host: Mouse
Reactivity: Human
Applications: IHC
Product overview
Code
BT-MCA4790
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
1H10D2
Immunogen
Purified recombinant fragment of SNCG expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
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