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Product > Antibody > CIB1 Monoclonal Antibody
CIB1 Monoclonal Antibody
CIB1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5A1F5E12
Host: Mouse
Reactivity:Human
Applications: WB,IHC
Product Summary
Size:
50μL
Clonality: 5A1F5E12
Host: Mouse
Reactivity: Human
Applications: WB,IHC
Product overview
Code
BT-MCA2247
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5A1F5E12
Immunogen
Purified recombinant fragment of CIB1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
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