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Home > Product > Antibody > CIB1 Monoclonal Antibody

CIB1 Monoclonal Antibody

CIB1 Monoclonal Antibody

Product Summary

Size: 50μL

Clonality: 5A1F5E12

Host: Mouse

Reactivity:Human

Applications: WB,IHC

Product Summary

Size: 50μL

Clonality: 5A1F5E12

Host: Mouse

Reactivity: Human

Applications: WB,IHC

Product overview

Code

BT-MCA2247

Host

Mouse

Isotype

Mouse IgG1

Size

50μL

Clonality

5A1F5E12

Immunogen

Purified recombinant fragment of CIB1 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Uniprot accession

Gene ID

10519

Synonyms

CIB;KIP;KIP1;SIP2-28

Research area

Signal transduction

Target protein

CIB1

Protocols

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Product size

Price

  • 50μL

    $220.00

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Lead time: Within one week

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