Code
BT-MCA3641
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
8F12C6B8
Immunogen
Purified recombinant fragment of human ApoM expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein(about 21kDa), is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment. Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.
Uniprot accession
Molecular weight
21kDa
Gene ID
55937
Synonyms
G3a;NG20;HSPC336;MGC22400
Research area
Signal transduction,Metabolism,Cardiovascular
Target protein
ApoM
